News For Alzheimer’s And Dementia Caregivers
We have entered a new era of improved and emerging biologically-based diagnostic biomarkers for Alzheimer's disease (AD) and AD-related neurodegenerative disorders (ADRD) that are rapidly impacting evaluation and care paradigms in every clinical setting: primary care, specialty care and dementia subspecialty care....
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Published on: 12-23-24
A new gene editing tool that helps cellular machinery skip parts of genes responsible for diseases has been applied to reduce the formation of amyloid-beta plaque precursors in a mouse model of Alzheimer's disease, researchers at the University of Illinois Urbana-Champaign report....
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Published on: 12-23-24
Researchers with the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have unveiled a critical mechanism that links cellular stress in the brain to the progression of Alzheimer's disease (AD)....
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Published on: 12-23-24
The holiday spirit is infectious, even for people suffering from dementia....
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Published on: 12-23-24
Alzheimer's disease (AD) is a debilitating neurodegenerative disorder associated with a progressive decline in memory and mental abilities, which can significantly hinder people's ability to complete daily tasks. Past studies found that patients diagnosed with AD, as well as some other neurodegenerative disorders, exhibit an abnormal accumulation of tau protein...
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Published on: 12-22-24
Can simple diet and lifestyle changes keep your brain healthy? Do you have the power to prevent Alzheimer's disease and dementia or lower your MS risks?...
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Published on: 12-20-24
Alzheimer’s disease is a progressive neurological disorder, causing problems with memory, thinking, and behavior. It is the most common form of dementia, affecting an estimated 6.7 million Americans aged 65 and older, and is the sixth leading cause of death in the nation. Two-thirds of those with Alzheimer’s disease in...
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Published on: 12-20-24
Researchers at the Warren Center for Neuroscience Drug Discovery, a clinical stage biotech within the Vanderbilt University School of Medicine Basic Sciences, have detailed the successful drug discovery of a phase I single ascending dose clinical trial of VU319, a drug for memory loss in people with Alzheimer's disease and...
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Published on: 12-19-24
A new study has demonstrated for the first time how and why music can reduce distress and agitation for people with advanced dementia....
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Published on: 12-19-24
Arizona State University and Banner Alzheimer's Institute researchers, along with their collaborators, have discovered a surprising link between a chronic gut infection caused by a common virus and the development of Alzheimer's disease in a subset of people....
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Published on: 12-19-24
A new Rice University study sheds light on the critical role marital relationships play in the mental and physical health of caregivers for spouses living with dementia, revealing that caregiver mental health dramatically improves when caregivers feel supported, understood and appreciated by their loved ones requiring care....
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Published on: 12-18-24
For healthy older adults, using antibiotics is not associated with an increased risk of cognitive impairment or dementia, according to a study published in the December 18, 2024, online issue of Neurology....
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Published on: 12-18-24
To identify and follow blood vessel-related changes in the brain that contribute to cognitive impairment and dementia, researchers and clinicians typically rely on MRI to evaluate 'downstream' biological markers -- those at the end of a cascade of events. But a new multicenter study could lead to a cost-effective blood...
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Published on: 12-18-24
Women born in the most sexist U.S. states experience faster memory decline in later years compared to women born in the least sexist states, a new study by researchers at Columbia University Vagelos College of Physicians and Surgeons has found. The work appears in Alzheimer's & Dementia....
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Published on: 12-18-24
To identify and follow blood vessel-related changes in the brain that contribute to cognitive impairment and dementia, researchers and clinicians typically rely on MRI to evaluate "downstream" biological markers—those at the end of a cascade of events. But a multicenter study led by UCLA researchers could lead to a cost-effective...
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Published on: 12-18-24
Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases at UT Health San Antonio, Boston University School of Medicine and the Framingham Heart Study have found that higher scores on the Dietary Inflammatory Index (DII) are associated with an increased incidence of all-cause dementia and Alzheimer's disease (AD) dementia....
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Published on: 12-17-24
Holidays are a time for families and friends to gather, but for older people with Alzheimer's disease and other dementias, it can cause so much stress and confusion that they could be in danger of what experts calls wandering....
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Published on: 12-17-24
A new study raises the possibility that jobs that require frequent spatial processing—such as figuring out a taxi route or the best way to navigate to a hospital—could lead to lower rates of death from Alzheimer's disease. Researchers from Mass General Brigham investigated this possibility by using national data on...
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Published on: 12-16-24
Progressive supranuclear palsy (PSP) is a severe and rapidly progressing neurodegenerative disease that affects both motor and cognitive functions. Often misdiagnosed or underdiagnosed due to a lack of specific biomarkers, PSP has posed significant challenges for accurate diagnosis and treatment. However, a new study published in the journal Alzheimer's &...
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Published on: 12-16-24
Adapting activities for individuals with Alzheimer's disease is essential for maintaining their engagement and well-being. As Alzheimer's progresses, activities that were once routine can become challenging. Here's how caregivers can help loved ones enjoy meaningful and fulfilling experiences....
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Published on: 12-16-24
It's that time of the year when most of us get the chance to sit back and enjoy some well-deserved down time. But whether you reach for the TV control, or a favorite book, your choice could have implications for your long-term brain health, say researchers at the University of...
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Published on: 12-16-24
It's that time of the year when most of us get the chance to sit back and enjoy some well-deserved down time. But whether you reach for the TV controller, or a favorite book, your choice could have implications for your long-term brain health, say researchers....
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Published on: 12-15-24
Microglia are known to play an important role in Alzheimer's disease, but exactly what they do has remained a mystery. Scientists in the Bart De Strooper Lab at the VIB-KU Leuven Center for Brain & Disease have unraveled the varying roles of microglia in Alzheimer's at different stages of the...
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Published on: 12-13-24
Many people could greatly improve their odds against developing dementia by making four, low-cost lifestyle changes, Western researchers have discovered....
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Published on: 12-12-24
A team from the University of North Texas Health Science Center at Fort Worth has conducted the largest characterization of plasma neurofilament light chain (NfL) in community-dwelling non-Hispanic Blacks. The study is published in the Journal of Alzheimer's Disease....
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Published on: 12-11-24
Globally, approximately 139 million people are expected to have Alzheimer's disease (AD) by 2050. Magnetic resonance imaging (MRI) is an important tool for identifying changes in brain structure that precede cognitive decline and progression with disease; however, its cost limits widespread use....
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Published on: 12-10-24
By 2050, around 135 million people worldwide will be living with dementia. The most common cause of dementia is Alzheimer's disease. Women are more likely than men to develop Alzheimer's disease, even after accounting for women living longer....
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Published on: 12-10-24
More than 982,000 individuals in the U.K. are currently living with dementia, a condition that gradually erodes cognitive functions and can significantly impact daily life....
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Published on: 12-10-24
Astrocytes are star-shaped glial cells in the central nervous system that support neuronal function, maintain the blood-brain barrier, and contribute to brain repair and homeostasis. The evolution of these cells throughout the progression of Alzheimer's disease (AD) is still poorly understood, particularly when compared to that of neurons and other...
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Published on: 12-10-24
A study by the team of Prof. Kristel Sleegers (VIB-UAntwerp), published in Acta Neuropathologica, has offered new insights into the genetic factors that drive Alzheimer's disease. Using samples from the Leuven Brain Collection, the researchers linked certain genes not only to hallmark features like tau tangles and amyloid plaques but...
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Published on: 12-09-24
A team of UVM scientists led by Mark Nelson, Ph.D., from the Larner College of Medicine at the University of Vermont, has uncovered a novel mechanism that reshapes our understanding of how blood flow is regulated in the brain. The study, published in The Proceedings of the National Academy of...
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Published on: 12-09-24
A new study has found no evidence that common modifiable health and lifestyle risk factors are responsible for the elevated dementia risk observed among former professional soccer players....
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Published on: 12-09-24
A major UK study into the effectiveness of a World Health Organization's (WHO) online resource for caregivers of people living with dementia has revealed disappointing results....
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Published on: 12-09-24
Cleveland Clinic Genome Center researchers have unraveled how immune cells called microglia can transform and drive harmful processes like neuroinflammation in Alzheimer's disease. The study, published in the journal Alzheimer's & Dementia, also integrates drug databases with real-world patient data to identify FDA-approved drugs that may be repurposed to target...
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Published on: 12-06-24
Stroke survivors have an 80% increased risk of dementia compared to people who've never suffered a stroke, a new study finds....
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Published on: 12-06-24
“Every dime was well spent,” said John Reichart, who decorated his street in Indianola, Iowa for his wife, Joan....
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Published on: 12-05-24
Inhibiting TLR7, an immune signaling protein, may help preserve the protective layer surrounding nerve fibers in the brain during both Alzheimer's disease and ordinary aging, suggests a study led by researchers at Weill Cornell Medicine. The research is published in the journal Science....
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Published on: 12-04-24
Researchers at Columbia University Mailman School of Public Health have developed a novel computational pipeline designed to identify protein biomarkers associated with complex diseases, including Alzheimer's disease (AD). This innovative tool analyzes biomarkers that can induce 3D structural changes in proteins, providing critical insights into disease mechanisms and highlighting potential...
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Published on: 12-04-24
Researchers from Saint Michael's College and the University of Vermont have made a new discovery that provides a better understanding of how Alzheimer's disease develops in the human brain....
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Published on: 12-03-24
Patients with frontotemporal dementia often lack the ability to empathize. A study has now shown that these patients do not show the same brain activity as healthy individuals when they witness the pain of others, a finding that it is hoped will increase understanding of this specific dementia disease....
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Published on: 12-03-24
Patients with frontotemporal dementia often lack the ability to empathize. A study at Karolinska Institutet has now shown that these patients do not show the same brain activity as healthy individuals when they witness the pain of others, a finding that it is hoped will increase understanding of this specific...
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Published on: 12-03-24
Alzheimer's disease is a debilitating condition that slowly robs people of their memory and cognitive abilities, affecting millions of people worldwide. Familial Alzheimer's disease (FAD), a rare inherited form of the disease, is linked to mutations in several genes, including APP, PSEN1, and PSEN2. The impact of PSEN2 mutations has...
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Published on: 12-03-24
The risk of developing dementia later in life is strongly predicted by a person's cognitive ability, functional limitations and physical health as many as 20 years before onset of the illness, according to a new RAND report....
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Published on: 12-03-24
Researchers have linked a specific type of body fat to the abnormal proteins in the brain that are hallmarks of Alzheimer's disease up to 20 years before the earliest symptoms of dementia appear, according to a new study. The researchers emphasized that lifestyle modifications targeted at reducing this fat could...
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Published on: 12-02-24
Ketone bodies, produced by the body to provide fuel during fasting, have roles in regulating cellular processes and aging mechanisms beyond energy production. Research at the Buck Institute shows that ketone bodies can best be understood as powerful signaling metabolites affecting brain function in aging and Alzheimer's disease....
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Published on: 12-02-24
Researchers have linked a specific type of body fat to the abnormal proteins in the brain that are hallmarks of Alzheimer's disease up to 20 years before the earliest symptoms of dementia appear, according to a study being presented at the annual meeting of the Radiological Society of North America...
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Published on: 12-02-24
After strange doings next door, an elderly neighbor vanishes — then reappears angry and confused on their doorstep....
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Published on: 11-29-24
The U.K.'s leading hearing loss organizations have joined forces to highlight misleading reports by some health professionals and the media that hearing loss causes dementia, and treating hearing loss will reduce our individual risk of dementia....
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Published on: 11-29-24
When Dad first started forgetting things, I thought I’d lost him. I didn’t imagine I’d have more of him than I did before....
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Published on: 11-29-24
Alzheimer's disease is one of the world's biggest health problems. Yet, despite the fact millions of people globally are diagnosed with the disease each year, it remains a challenge to treat. This is largely because the underlying causes are still not fully understood....
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Published on: 11-28-24