A class of drugs for diabetes may be associated with a lower risk of dementia and Parkinson's disease, according to a new study....
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Published on: 09-18-24
A class of drugs for diabetes may be associated with a lower risk of dementia and Parkinson's disease, according to a study published in the September 18, 2024, online issue of Neurology....
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Published on: 09-18-24
New research is more closely linking obesity to dementia. Higher levels of leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting brain white matter in middle-aged adults, according to a study by The University of Texas Health Science Center at San Antonio (UT Health San...
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Published on: 09-18-24
A study more closely links obesity to dementia, finding that leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting brain white matter in middle-aged adults....
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Published on: 09-18-24
For years, many people with Alzheimer's disease have been diagnosed clinically and confirmed at autopsy. Now Alzheimer's disease pathology can be identified with relatively high accuracy via a blood test that has the potential for widespread use in practice....
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Published on: 09-18-24
Two new papers by a team of researchers demonstrate that evaluating microRNAs in blood can be used not only to diagnose mild cognitive impairment (MCI) but also, critically, to predict the conversion from MCI to dementia due to Alzheimer's disease. Moreover, the researchers uncovered microRNA candidate molecular biomarkers that associate...
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Published on: 09-18-24
In the ever-evolving field of Alzheimer's disease research, the development of disease-modifying therapies has sparked both excitement and debate. While these therapies represent a promising shift in the treatment landscape, questions remain about their clinical benefits, risks and economic impact. The controversies surrounding these therapies have led to apprehension among...
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Published on: 09-18-24
The failure to diagnose Alzheimer's disease—the most common form of dementia in the elderly—at an early stage of molecular pathology is considered a major reason that treatments fail in clinical trials. Previous research to molecularly diagnose Alzheimer's disease yielded "A/T/N" central biomarkers based on the measurements of proteins, β-amyloid ("A")...
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Published on: 09-18-24
Amyloid-beta and tau proteins have long been associated with Alzheimer's disease. The pathological buildup of these proteins leads to cognitive decline in people with the disease. How it does that, though, remains poorly understood....
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Published on: 09-18-24
Medical researchers conducted the largest-ever genome-wide association study of all-cause dementia, finding substantial genetic overlap with vascular dementia....
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Published on: 09-17-24
In landmark research, scientists at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have reported the largest-ever genome-wide association study of dementia from all causes, revealing an overlap of genetic risks including neurodegeneration, vascular factors and cerebral small-vessel disease....
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Published on: 09-17-24
A team of epidemiologists at the First Hospital of Hebei Medical University, in China, has shown experimental evidence of an inverse relationship between incidences of Alzheimer's disease and colorectal cancer....
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Published on: 09-17-24
Research using participants from one of Australia's largest and longest running studies of aging has looked at the impact of mild cognitive impairment and dementia on a person's ability to interact in social contexts....
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Published on: 09-16-24
A new Research Letter published in Palliative Medicine estimates that the palliative care needs of people living with dementia in England and Wales will be much higher by 2040 than previous projections have indicated....
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Published on: 09-16-24
Scientists have developed new potential therapies that selectively remove aggregated tau proteins, which are associated with Alzheimer's disease, and improve symptoms of neurodegeneration in mice....
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Published on: 09-13-24
He produced an early photo book about what he called the first “rock ’n’ roll war,” documented his grandfather’s dementia and became a filmmaker....
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Published on: 09-12-24
Patients regularly show up at university hospitals with diseases so rare and specific as to be scarcely known to physicians in private practice. Primary 4-repeat tauopathies are a good example. These are diseases which are primarily associated with movement disorders, but with symptoms that can often resemble those of Alzheimer's...
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Published on: 09-12-24
A lack of diversity in genomic studies for dementia could limit the effectiveness of targeted therapies across underrepresented populations, finds research by UCL experts....
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Published on: 09-11-24
Researchers have for the first time identified degeneration-associated "molecular markers"—observable changes in cells and their gene-regulating networks—that are shared by several forms of dementia that affect different regions of the brain....
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Published on: 09-11-24
A study published in the journal Brain shows that increases in protein levels with new Alzheimer's drugs can explain the slowing of cognitive impairment at least as well as the reduction in amyloid plaques....
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Published on: 09-11-24
Francisco Lopera defied rebels, cartels and vampire bats to become a pioneering researcher of Alzheimer’s disease....
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Published on: 09-11-24
The UC Davis School of Medicine received $400 million in external research awards in fiscal year 2023-24. These federal, state and industry awards fund cutting edge medical and health research....
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Published on: 09-10-24
The UC Davis School of Medicine received $400 million in external research awards in fiscal year 2023-24. These federal, state and industry awards fund cutting edge medical and health research....
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Published on: 09-10-24
The aging process can lead to diminished cognitive functioning for older adults. In addition, about 10 percent of people previously diagnosed with mild cognitive impairment develop Alzheimer's disease or other forms of dementia every year....
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Published on: 09-10-24
Findings from a new study suggest that older people with mild cognitive impairment who engage in high levels of activities such as word games and hobbies have better memory, working memory, attention and processing speed than those who do not....
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Published on: 09-10-24
There's no question we've reached a turning point for Alzheimer's disease treatment....
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Published on: 09-10-24
As the median age of our population rises, so does the number of people diagnosed with Alzheimer's disease. With advances in technology, it's easier to determine brain age and identify blood-based Alzheimer's disease biomarkers. A new study links trauma exposure with brain age blood markers of risk for Alzheimer's disease....
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Published on: 09-10-24
People with dementia are more likely to have suicidal thoughts but are not necessarily more likely to attempt or die by suicide than the general population, finds a new study led by UCL researchers....
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Published on: 09-09-24
Laboratory mice with cognitive issues including Alzheimer's disease showed improved memory skills within a couple of weeks of treatment with a new medicine tested at Colorado State University....
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Published on: 09-09-24
Older adults who are more vulnerable to financial scams may have brain changes linked to a higher risk of Alzheimer's disease, according to a first-of-its-kind study led by researchers at the USC Dornsife College of Letters, Arts and Sciences....
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Published on: 09-06-24
Can training your brain to remember things help you ward off the symptoms of Alzheimer's disease? A new Canadian study suggests that yes, it can—even five years after you received the training....
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Published on: 09-06-24
The Emory Goizueta Brain Health Institute (GBHI) has prioritized involving African American volunteers in its research, working to create more inclusive tools for diagnosing Alzheimer's disease and related disorders. Today, about half of the Institute's new volunteers are African American....
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Published on: 09-06-24
A study from Karolinska Institutet, published in the journal Molecular Psychiatry, offers new insights into the progression of Alzheimer's disease (AD). The research reveals critical differences in the progression of memory loss based on the presence of specific proteins in the brain....
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Published on: 09-06-24
Prior research has found that there may be a connection between hearing loss in aging people and the onset of dementia. In a new study, a team of health care researchers and geriatric specialists affiliated with Johns Hopkins Bloomberg School of Public Health, the University of Michigan and the Duke...
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Published on: 09-06-24
People living with dementia should have more power and creative freedom in collaborative design projects, new research from Heriot-Watt University suggests....
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Published on: 09-05-24
New research has discovered a unique and promising avenue for diagnosing Alzheimer's disease (AD) earlier—by analyzing AD biomarkers in blood—so that the impacts of dementia can be reduced....
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Published on: 09-05-24
Despite more than half of all residents in aged care having dementia, tools designed to improve quality of care across the sector are likely not meeting their needs, new research has found....
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Published on: 09-05-24
Research discovered a unique and promising avenue for diagnosing Alzheimer's disease (AD) earlier -- by analyzing AD biomarkers in blood -- so that the impacts of dementia can be reduced. The researchers applied inorganic analytical geochemistry techniques, originally developed for cosmochemistry -- for example, to study the formation and evolution...
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Published on: 09-05-24
Among progressive neurodegenerative diseases, Alzheimer's is one of the most common and most heartbreaking. It robs individuals of their memories and self-sufficiency and can even alter their personalities....
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Published on: 09-05-24
A Korean study published recently suggests that people with type 2 diabetes who are prescribed a particular class of drug might be at a significantly lower risk of dementia....
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Published on: 09-04-24
Cognitive decline and dementia can stem from illnesses like Alzheimer's disease and conditions like hypertension that damage blood vessels in the brain. People with both may have an even greater risk of developing cognitive impairment, a new Yale study finds....
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Published on: 09-04-24
In a recent development in Alzheimer's disease research, Auburn University scientists have studied a new drug, troriluzole, that can prevent brain changes leading to memory loss and cognitive decline in a mouse model of the disease. This study, published in the Journal of Neurochemistry, is the first to show how...
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Published on: 09-04-24
New research from the University of Kentucky's Sanders-Brown Center on Aging shows compelling evidence that the cognitive impairments observed in long COVID patients share striking similarities with those seen in Alzheimer's disease and related dementias....
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Published on: 09-02-24
A simple blood test to diagnose Alzheimer's disease, which afflicts nearly 7 million Americans, could soon replace more invasive and expensive diagnostic methods such as spinal taps and brain scans....
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Published on: 08-31-24
In a study recently published in Alzheimer's & Dementia, researchers at Karolinska Institutet and Shandong Provincial University have reported the polygenic risk scores (PRS) with and without apolipoprotein E (APOE) gene that were associated both cross-sectionally and longitudinally with around double risk of Alzheimer's disease. Moreover, the PRS, in combination...
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Published on: 08-30-24
Columbia University researchers have discovered how variants of the ABCA7 gene, which are common among Black Americans, increase the risk for Alzheimer's disease. The paper is published in the journal Cell Genomics....
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Published on: 08-30-24
People can create many special moments if they include a loved one with dementia in their end-of-summer Labor Day getaway....
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Published on: 08-30-24
In some people, new-onset depression may stem from the same buildup of toxic plaques in the brain that have long been linked to Alzheimer's disease, according to a new study....
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Published on: 08-30-24
Karolinska Institutet has discovered that an already registered antidepressant, duloxetine, may also have positive effects on memory and cognitive functions in the elderly....
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Published on: 08-29-24